The Cancer Research Unit conducts trailblazing work on telomeres, which are important for senescence (aging) and all cancers.

Research in the Cell Biology Unit focuses on one of the major factors in at least 85% of all cancers affecting children and adults: the molecule telomerase.

The Cell Signalling Unit studies the detailed molecular mechanisms of how signals are sent from one cell to another in the body and how this impacts a range of diseases.

The Computational Systems Biology Group focuses on developing computational and statistical models to reconstruct molecular networks and model their regulations in various cell systems and diseases.

The Embryology Unit studies how development occurs in order to understand what goes wrong in birth defects. Current research focuses on the cellular and molecular mechanisms of body patterning during mouse development.

The Eye Genetics Research Unit aims to understand the genetic causes contributing to blinding eye diseases to improve the diagnosis and treatment of these conditions.

The Gene Therapy Research Unit finds ways to correct genetic diseases in children. They are a joint initiative of Children’s Medical Research Institute and The Children’s Hospital at Westmead (SCHN).

The Genome Integrity Unit investigates how cells maintain their DNA health with specific interests in cancer and early development.

The ACRF International Centre for the Proteome of Human Cancer

The Stem Cell Medicine Group focuses on two complementary fields of research: stem cells and regenerative medicine. Our aim is to disseminate and increase translational stem cell research and utilise the great potential of regenerative medicine for childhood disease.

In the Synapse Proteomics Group, we are focused on answering fundamental questions, such as how does the brain work? And at the same time asking how a disease state can upset brain function. This fundamental knowledge is then applied to identify new potential drug targets.

The Telomere Length Regulation Unit focuses on understanding the molecular mechanisms underlying telomere length regulation and how telomere length can be manipulated to control cell division.

In the Translational Vectorology Unit, we are “translational tool makers” as we develop and improve vector-based tools that can be used in a wide range of basic and preclinical studies, as well as in clinical applications.

The Nuclear Dynamics Group investigates how cells attempt to re-organise cellular architecture to resolve threats on genome stability.

The Neuromuscular Gene Discovery Group is part of the Kids Neuroscience Centre at the Children’s Hospital at Westmead (CHW) and comprises a large multidisciplinary team devoted to identifying the causes, consequences, and therapies for patients with inherited neuromuscular disorders.

The Molecular Neurobiology Lab at Kids Research, Westmead Children's Hospital has been studying the pathogenic mechanisms of Rett syndrome for the past 9 years and conducts a program of interdisciplinary research spanning fields of neurology, neuropathology, fundamental neuroscience, clinical chemistry, and pharmacology.